The mean tumor size was 5.5 cm, and the presence of cirrhosis was confirmed by pathological histology in 196 (66.2%) patients, with higher AFP levels (p < 0.001), higher PLT levels (p = 0.026) and more patients with BCLC stage 0 or A (p = 0.005) in the antiviral treatment group compared with the non-antiviral group. This evidence concerns the gene AFP and neoplasm.