Neuroblastoma is expected to express PARP1 at levels twice that of solid tumors in adults33, and we have demonstrated this in pre-clinical models where peak uptake with [18F]FTT was 2 to 4% ID/g in breast cancer models HCC1937 and MDA-MB-23134, while [211At]PTT uptake was 10 to 15% ID/g for neuroblastoma models IMR-053 and NB-EBC1 (this work). The gene discussed is PARP1; the disease is neuroblastoma.