Their compounds displayed anti-TB activity against both active and nutrient-starved dormant Mtb cells with MIC range from 1.53 to 60.38 μM, and the 2-ethyl-N-phenethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyridin-4-amine inhibited AlaDH with IC50 of 1.82±0.42 μM and revealed 2.7 log reduction of dormant Mtb cells at 10 μg/ml by showing more potency than isoniazid and rifampicin [69]. Here, ALAD is linked to tuberculosis.