Regarding “Workplace very dusty: Sometimes” (that has a causal effect on “Condition that has ever been diagnosed by a doctor: Emphysema or chronic bronchitis”) the most statistically significant pathway is “Translation synthesis by REV1”, p value = 0.010, gene involved: REV1 DNA directed polymerase (REV1, related to rs115051693, an intronic variant) [19]. Here, REV1 is linked to chronic bronchitis.