SHH and respiratory system disorder: Our results showed that the most statistically significant pathway related to “Transport type for commuting to job workplace: Car or motor vehicle” (with causal effect on “Diseases of the respiratory system” and “Other pulmonary diagnosis”) is "HHAT G278V non-palmitoyl Hh-Np," (i.e., the Sonic Hedgehog (SHH) morphogen pathway).