SOX2 and glioblastoma: Superenhancer-associated genes across 11 glioblastoma tissues included EGFR, POUF3, SOX2, and AVIL, which were each previously shown to contribute to glioblastoma tumorigenesis (Supplemental Figure 1A; supplemental material available online with this article; https://doi.org/10.1172/JCI163592DS1).