HNRNPA2B1 and lung cancer: Since GGAG is one of the most typical EXO-motifs present in many exosomal miRNAs, including miR-1246 (Villarroya-Beltri et al. 2013; Wei et al. 2021), and is bound by hnRNPA2B1 protein, which was i.e. shown to selectively guide miRNA-155-5p packaging into lung cancer EVs (Ingenito et al. 2019; Li et al. 2021), we decided to explore whether it can also mediate miR-1246 transfer into exosomes.