Several published studies have investigated different aspects of DAT imaging with the relatively new, highly selective DAT tracer [18F]-(E)-N-(3-iodoprop-2-enyl)- 2β-carbofluoroethoxy-3β-(4'-methyl-phenyl) nortropane (FE-PE2I) [15] in parkinsonian disease and in healthy individuals [16–24]. This evidence concerns the gene SLC6A3 and Parkinsonism.