APOE and Alzheimer disease: For the application data set from the ADNI cohort, significant differences in years of education, MMSE, CDR‐SB, and APOE ε4 carriers are observed between the NC1 and AD groups (p < .001), while the MCI group exhibits differences in sex, MMSE, CDR‐SB, and APOE ε4 carrier compared with the NC1 group (sex: p = .003; APOE ε4 carrier: p = .003; MMSE and CDR‐SB: p < .001).