Population‐based genetic analysis using different tissues (adipose visceral omentum, skeletal muscle, mammary tissue, testis, subcutaneous adipose, prostate, tibial nerve and artery, and pituitary and brain) found that East Asian populations had higher allele frequencies in expression quantitative trait loci variants associated with increased ACE2 expression compared to Admixed American, African, European and South Asian populations, suggesting differential response to COVID‐19.165. The gene discussed is ACE2; the disease is COVID-19.