Mutations significantly enriched in both AML‐MRC‐H and AML‐MRC‐M relative to AML‐MRC‐C were in ASXL1 (p = 0.011 and p = 0.0008, respectively), SRSF2 (p < 0.0001 and p < 0.0001, respectively) and IDH2 (p = 0.041 and p = 0.0021, respectively). This evidence concerns the gene SRSF2 and acute myeloid leukemia.