To explore specific mutations that may be associated with VSIR expression, we chose to only study NRAS, DNMT3A, IDH1, TET2, NPM1, WT1, FLT3, IDH2, TP53, CEBPA, and RUNX1 mutations, which are all present in greater than 5% of AML samples in the TCGA dataset. The gene discussed is WT1; the disease is acute myeloid leukemia.