GPX4 and carotid atherosclerosis: A study has shown that ferrostatin-1 (Fer-1), a ferroptosis inhibitor, increases the expression of SLC7A11 and GPX4 by reducing the accumulation of iron in cells, thus decreasing the accumulation of lipid ROS, eliminating lipid peroxidation and endothelial cell damage, and inhibiting the development of carotid atherosclerosis [23].