Since loss of Elongator correlates with poor acetylation of α-tubulin lysine 40 (K40) in neuronal MTs (Creppe et al., 2009; Solinger et al., 2010), a defect shared by Elp1 KD neuroblastoma cells (Supplementary Figure S2A), we tested whether Tau hypoacetylation may arise from a change of expression or activity of Hdac6, the enzyme that also controls α-tubulin deacetylation (Kalebic et al., 2013). The gene discussed is MAPT; the disease is neuroblastoma.