Our FD neuroblastoma cell model, where Elp1 is knockdown, shows transcriptional changes and aberrant cell shape, expressed as cell adhesion problem that results from Contactin 1 overexpression, including distinct neurite process formation as well as disorganization and instability of microtubules (MTs) (Cohen-kupiec et al., 2010; Cheishvili et al., 2011; Cohen-Kupiec et al., 2011). This evidence concerns the gene ELP1 and neuroblastoma.