WNT5A and breast cancer: In agreement with our results, the aberrant methylation of other genes involved in the Wnt signaling pathway (e.g., WNT5A and WNT7A) has previously been described in tumor cells from the BC luminal subtype (Shan et al., 2019) and in other tumor types, such as gastric cancer or chronic lymphocytic leukemia (Liu et al., 2019; Poppova et al., 2022).