In the last decade, a growing body of evidence has implied an emerging tumor suppressing role of PAX1 in various human cancers, including cervical cancer (Huang et al., 2010; Kan et al., 2014; Lai et al., 2014; Liu H. et al., 2020; Li et al., 2021), ovarian cancer (Hassan et al., 2017), colorectal carcinoma (Huang et al., 2017), parathyroid tumor (Singh et al., 2022), as well as oral squamous cell carcinoma (Huang et al., 2014; Cheng et al., 2018; Sun et al., 2020), and so on. The gene discussed is PAX1; the disease is cervical carcinoma.