Eilertsen et al. found that aberrant splicing resulting in low expression of the KRAS4A transcript variant, in relation to the KRAS4B transcript, was associated with increased KRAS signaling and poor patient prognosis specifically in KRAS wild-type MSS CRC suggesting that KRAS splicing is of prognostic relevance in KRAS wild-type CRC (Eilertsen et al., 2019). The gene discussed is KRAS; the disease is colorectal carcinoma.