Figure 1 shows that injection of NAc, which binds to the lectin-like domain of TNF (9, 10) into the joints of mice subjected to mBSA arthritis, caused a trend to increased cell counts—albeit not statistically significant—measured after 7 h in joint exudates, with a predominance (>85%) of polymorphonuclear cells (Figures 1A–D). Here, TNF is linked to arthritic joint disease.