A study with 3 patients with pSS-associated thrombocytopenia, 3 pSS patients with normal platelets and 3 healthy controls, revealed increased TLR7 and IL-8 expression in B cells of pSS-associated thrombocytopenia compared to pSS patients without thrombocytopenia or healthy controls (104). This evidence concerns the gene CXCL8 and Thrombocytopenia.