Evaluation of autoimmunity in female MyD88-deficient MRL/lpr (MyD88-/- MRL/lpr) mice at 24 weeks of age revealed reduced severity of salivary gland inflammation and serum titers of anti-dsDNA autoantibodies, as well decreased autoimmune nephritis, compared to MD88+/- MRL/lpr mice (88). Here, MYD88 is linked to Autoimmunity.