IFNA1 and viral infectious disease: Intriguingly, vsRNAs with 22 nt in length appeared to be of the most abundant among those distributed along the antisense of SARS-CoV-2 viral genome in Calu-3 and A549-hACE2 cells, the IFN-competent cell lines, after 24 hours viral infection (Figure S4 and Table 1) (33, 60).