Among the 8 TRPCG, UCN, FJX1, TIPM1, and PCOLCE2 were negatively associated with OS of CRC patients (HR > 1), while CD177, PPARGC1A, CLDN23, and MTOR4 were positively associated with OS of CRC patients (HR< 1). The gene discussed is PPARGC1A; the disease is colorectal carcinoma.