CCL2 and infection: Interestingly, only GRA-o had a further significant up-regulation of Il12a. Overall, genes from cytokine storm and associated pathways (Ccl2, Ccl7 and Ccl12) were found to be differentially regulated in infections of L, G, GR, GRY-α, and GH-β while not as strongly involved in V and GK-δ.