• Eosinophilia develops bevor patency • Eotaxin-1 KO mice: higher adult worm burden • Same eosinophil counts, reduced eosinophil activation • IL-5 KO, IL-5 transgenic + dblGATA mice: eosinophilia associated with adult worm and MF clearance and nodule formation • MBP + EPO KO mice: increased adult worm burden • Traps contribute to MF clearance in vivo. Here, EPO is linked to Increased total eosinophil count.