In addition, immunofluorescence analysis of HNSCC samples showed the co-localization of CD68 and CD3/TCRα on the cell membrane, respectively (Figure 4C; Supplementary Figure 3A), and these cells were usually isolated in areas with high concentrations of T cells, suggesting the association between this group of cells and T cells. This evidence concerns the gene TRAC and head and neck squamous cell carcinoma.