For example, miRNA-200 family members (hsa-miR-200a-3p, hsa-miR-200b-3p, hsa-miR-200c-3p, and hsa-miR-141-3p), which are reported as tumor-suppressive group of miRNAs with essential role in suppressing EMT, were downregulated miRNAs (among the targeting miRNAs) in patients with higher expression of CNTN1, GPX3, FCN1 and SERPINE1 (NRGPI-high) (66). Here, SERPINE1 is linked to neoplasm.