CD8A and neoplasm: The results of this study also showed that BMs of CRPC have higher immune scores and more macrophages than the primary focus, but the number of CD8+ T cells (EPIC & TIMER) and activated NK cells (CIBERSORT) in BMs is lower, with more M2 macrophages, T regulatory cells (CIBERSORT) and tumor related fibroblasts (ssGSEA & EPIC).