Interestingly, Choi and colleagues novelly fused IL-7 with an Fc fragment to enhance the mucosal delivery across the genital epithelial barrier (Figure 4D), aiming at testing the antitumor effects of intravaginal administration of Fc-Fused IL-7 in combination with human papillomavirus (HPV) DNA vaccines against cervical cancer (80). This evidence concerns the gene IL7 and cervical cancer.