This interaction is of particular importance since the WAVE regulatory complex controls cytoskeletal remodeling (essential during cell migration), and WAVE complex components, such as CYFIP2, are linked to neurodevelopmental disorders (Takenawa and Miki, 2001; Tai et al., 2010; Abekhoukh and Bardoni, 2014; Chen et al., 2014). Here, WASF1 is linked to neurodevelopmental disorder.