In analyses adjusted for demographic characteristics and comorbidities (Table 2), patients with ≥67% of albumin-corrected serum calcium measurements outside the 2.00–2.25 mmol/L (8.0–9.0 mg/dL) range had 3.5 times higher odds of developing CKD (adjusted OR, 3.46; 95% CI, 1.82–6.56; P < 0.001) compared with patients with <33% of albumin-corrected serum calcium measurements outside this range. This evidence concerns the gene ALB and chronic kidney disease.