Patients with CKD compared with controls had a higher proportion of albumin-corrected serum calcium measurements outside, above, or below the 2.00–2.25 mmol/L (8.0–9.0 mg/dL) range (57.9% vs 41.2%, P < 0.001; 30.1% vs 20.0%, P < 0.01; 27.8% vs 20.1%, P=0.09, respectively; Supplementary Figure 1A). The gene discussed is ALB; the disease is chronic kidney disease.