TRPV1 and Parkinson disease: Yuan used photothermal nanomaterials to control the opening of transient receptor potential cation channel subfamily V member 1 (TRPV1) channels on the surface of microglia to enhance phagocytosis by microglia and accelerate the phagocytosis and degradation of α-Syn, thereby ameliorating PD (Yuan et al., 2022; Figure 1).