Unique pathways of F-AD switch genes were associated with viral myocarditis, Hippo signaling pathway, endometrial cancer, insulin signaling, PI3K-AKT signaling, adherens junction, gap junction, cardiomyopathy, mTOR signaling, longevity, sphingolipid signaling, apoptosis, E. coli infection (Figure 3B; Supplementary Table S5). This evidence concerns the gene INS and escherichia coli infection.