The proteomics analysis showed that the levels of superoxide dismutase (SOD2) protein (Teglas et al., 2020), GFAP (Wang et al., 2021), and clusterin (De Miguel et al., 2021) were increased while Aβ40 (Rao et al., 2015) was decreased in AD mice after exercise. This evidence concerns the gene GFAP and Alzheimer disease.