MAPK1 and COVID-19: Its potential mechanism of action for the treatment of COVID-19 is anti-inflammatory, anti-SARS-CoV-2 (107, 108), mainly through the regulation of interleukin receptors (IL-1A, IL-1B, IL-2, IL-4, IL-6, IL-10), mitogen-activated protein kinase receptors (MAPK1, MAPK3, MAPK8, MAPK14), TNF and other significant targets, thus achieving the treatment of COVID-19 (109–112).