WNK2 and benign prostatic hyperplasia: Recent studies have demonstrated that UME attenuates testosterone propionate-induced benign prostate hyperplasia via its pro-apoptotic and anti-proliferative activities (25); inhibits Heliobacter pylori colonization synergistically, especially when used in combination with Rubus crataegifolius (26); and prevents anti-photoaging of the skin by activating antioxidant enzymes and inhibiting the mitogen-activated protein kinase pathways (27).