CXCL8 and Granuloma: We next interrogated the expression of genes encoding the six plasma biomarkers (HBEGF, IL-1RA, NAMPT, IL6, ANG2, and IL8) using our previously reported publicly available gene expression dataset (GSE157671) generated by NextGen sequencing of micro-dissected sarcoidosis granulomas within lung tissues (6) and mediastinal lymph nodes (11, 32).