FCGR2B and preeclampsia: Studies suggested that the FcγRIIB-nt645 + 25A/G gene polymorphism was also associated with pre-eclampsia and gestational hypertension, and compared to the FcγRIIB-nt645 + 25AG and/or GG genotype or the G allele, the FcγRIIB-nt645 + 25A genotype or A allele demonstrated a higher frequency in women with pre-eclampsia (52).