UBR5 expression was significantly increased in bladder urothelial carcinoma (BLCA), breast invasive carcinoma (BRCA), colon adenocarcinoma (COAD), esophageal carcinoma (ESCA), cholangiocarcinoma (CHOL), liver hepatocellular carcinoma (LIHC), Glioblastoma multiforme (GBM), head and neck squamous cell carcinoma (HNSC), lung squamous cell carcinoma (Figure 1). The gene discussed is UBR5; the disease is carcinoma of esophagus.