EA could accelerate capillary formation in the brain infarction area of MCAO rats through up-regulating EphB4 and EphrinB2 mRNA and increasing the level of Src and PI3K, manifesting that the formation of new vessels after EA was partly to regulated by EphB4/EphrinB2 mediated Src/PI3K signal pathway (52). This evidence concerns the gene EFNB2 and brain infarction.