Stroke survivors had significantly greater inter-hemispheric asymmetry for CRP streamlines in comparison to healthy individuals (CRP AsymmStroke = 0.69; AsymmHealthy = 0.91), indicating fewer streamlines on the lesioned compared to non-lesioned hemisphere, and those who were most impaired may have shown some increased compensatory connectivity of the contralesional CRP. The gene discussed is CRP; the disease is Stroke.