SYNE1 and neoplasm: The tumor volume in group US, ZD2767P, ZD2767P+US, CPG2, or CPG2+US did not differ from that in group Ctrl, i.e., no antitumor effect; the volume was shrunk in groups ZD2767P+CPG2 and ZD2767P+CPG2+US, with a smaller value in the latter group (A549: p < 0.0001, A549/DDP: p < 0.0001); the inhibitory rates in groups ZD2767P+CPG2 and ZD2767P+CPG2+US were 39.7% and 63.5% in A549 tumors and 50.0% and 70.1% in A549/DDP tumors, respectively.