In groups ZD2767P+CPG2 and ZD2767P+CPG2+US, the apoptosis level (TUNEL) in tumor tissues was increased, but the GPX4 level was decreased (A549: p < 0.0001 for each; A549/DDP: p < 0.0001 for each) (Figure 6 and S5). Here, GPX4 is linked to neoplasm.