Considering that a large number of cell proliferation-related pathways were independently enriched in IUGR pigs, and CCND1 as a core molecule was involved in the regulatory network of skeletal muscle development in IUGR pigs, the effect of transfection of tRF-Glu-TTC-047 mimic on the proliferation of porcine primary cells was evaluated. This evidence concerns the gene CCND1 and fetal growth restriction.