In this regard, the CGM metrics observed decrease in CV and TBR < 70 mg/dL and TBR < 54 mg/dL was noteworthy, which is remarkable given the risk factors for the development of hypoglycaemia associated with this condition (sudden-onset insulinopenia with subsequent need for titration of insulin therapy, impaired release of the counterregulatory hormones, age, and additional comorbidities). The gene discussed is INS; the disease is Hypoglycemia.