LCN2 and neonatal abstinence syndrome: demonstrated that high blood pressure and CV fibrosis, also characterized by galectin-3 (Gal3) and collagen (Col)-1 upregulation, induced by the “nephrectomy Aldo–salt (NAS) model,” are prevented in NGAL–KO mice, suggesting a direct link between NGAL and endocrine AH due to excess Aldo production (60).