Interestingly in the lipedema group, insulin (r=0.577; p=0.039), TNFα (r=0.741; p=0.004), total cholesterol (r=0.662; p=0.014) and LDL-C concentrations (r=0.693; p= 0.009) were positively associated with age while none of these correlations was significant for the control group (Figures 1A–D). This evidence concerns the gene TNF and Lipedema.