Regarding significant association between stromal and tumor PD-L1 scores, two types of combination sets integrating the prognostic effects of MDSCs and the PD-1/PD-L1 axis were defined as follows: 1) MDSCs, PD-1+/CD8+ TIL ratio, and stromal PD-L1 immune cell score (combined set I) and 2) MDSCs, PD-1+/CD8+ TIL ratio, and tumor PD-L1 H-score (combined set II). Here, CD8A is linked to neoplasm.