ROR1 and B-cell chronic lymphocytic leukemia: To examine whether ROR-1lo/- leukemic B cells also segregated within the leukemic area of the t-SNE map, ROR-1lo/- B cells manually gated on the CD5/ROR-1 bi-parameter plot of merged CLL specimens were further separated into CD79blo/CD5hi (population B, leukemic) and CD79bhi/CD5lo (population C, healthy) cells.