H2BC1 was not expressed in almost all tumor types (Figure S1A), while the other H2B genes were differentially expressed in cholangiocarcinoma, esophageal carcinoma, glioblastoma multiforme (GBM), head and neck squamous cell carcinoma, and cutaneous melanoma (Figures S1B–Q). Here, H2BC21 is linked to head and neck squamous cell carcinoma.