Studies have suggested that the high expression of ALDH1 in CRC is related to the Wnt/β-catenin pathway (82, 89, 90), hsa_circ_0001806/miR-193a-5p/, COL1A1 axis (89), PI3K/AKT/mTOR signaling pathway (91), CXCL2/CXCR2 axis (92), miR-200-ZEB1/SANI2 axis (88). This evidence concerns the gene ALDH1A1 and colorectal carcinoma.