PDLIM7 and viral infectious disease: In EBV-positive HL, viral infection of malignant tumor cells is characterized by the consistent expression of three EBV-associated viral proteins (EBNA1, LMP1, and LMP2A) and two noncoding RNAs (EBERs and BARTs) (67), which are believed to play important roles in tumorigenesis, including the regulation of proliferation, metastasis, immune escape, and apoptosis (70, 71).