ARHGAP31-AS1 was co-expressed with five AME-associated genes (LPAR2, ABCC1, ABCC4, TGFB2 and TFAP2), LINC00426 was co-expressed with five AME-related genes (IDO1, SIGLEC7, CD4, CTLA4 and LTA), LINC01116 was co-expressed with seven AME-associated genes (FABP5, PLAU, IL10, BIRC5, SLC38A5, GJA1 and NES), TMCC1-AS1 was co-expressed with six AME-related genes (G6PD, AKR1C1, PTK2, NPM1, TKT and AKR1). The gene discussed is AKR1C1; the disease is apparent mineralocorticoid excess.