Finally, we included 11 (8–12, 15, 16, 18, 28–30) different RCTs that met all the inclusion with the following outcomes: BMI (n = 9), energy, carbohydrate, and total fat intake (n = 4), FBS (n = 8), HbA1c (n = 3), insulin (n = 5), HOMA-IR (n = 5), hs-CRP (n = 9), hepatic features [steatosis (n = 4), and fibrosis (n = 4)], ALP (n = 3), ALT (n = 10), AST (n = 10), GGT (n = 8), TC (n = 10), TG (n = 10), LDL-C (n = 9), HDL-C (n = 9). The gene discussed is GPT; the disease is steatosis.